Targeting the epigenetic readers in Ewing Sarcoma inhibits the oncogenic transcription factor EWS/Fli1

Targeting the epigenetic readers in Ewing Sarcoma inhibits the oncogenic transcription factor EWS/Fli1

Ewing Sarcoma is a rare bone and soft tissue malignancy affecting children and young adults. Chromosomal translocations in this cancer produce fusion oncogenes as characteristic molecular signatures of the disease. The most common case is the translocation t (11; 22) (q24;q12) which yields the EWS-F...

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Bibliographic Details
Main Authors: Jacques, Camille, Lamoureux, François, Baud’huin, Marc, Calleja, Lidia Rodriguez, Quillard, Thibaut, Amiaud, Jérôme, Tirode, Franck, Rédini, Françoise, Bradner, James E., Heymann, Dominique, Ory, Benjamin
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029689/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029689/

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