Double-strand break repair and colorectal cancer: gene variants within 3′ UTRs and microRNAs binding as modulators of cancer risk and clinical outcome

Double-strand break repair and colorectal cancer: gene variants within 3′ UTRs and microRNAs binding as modulators of cancer risk and clinical outcome

Genetic variations in 3′ untranslated regions of target genes may affect microRNA binding, resulting in differential protein expression. microRNAs regulate DNA repair, and single-nucleotide polymorphisms in miRNA binding sites (miRSNPs) may account for interindividual differences in the DNA repair c...

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Bibliographic Details
Main Authors: Naccarati, Alessio, Rosa, Fabio, Vymetalkova, Veronika, Barone, Elisa, Jiraskova, Katerina, Di Gaetano, Cornelia, Novotny, Jan, Levy, Miroslav, Vodickova, Ludmila, Gemignani, Federica, Buchler, Tomas, Landi, Stefano, Vodicka, Pavel, Pardini, Barbara
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029617/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029617/

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