Efficacy and safety of eribulin mesylate in advanced soft tissue sarcomas

Efficacy and safety of eribulin mesylate in advanced soft tissue sarcomas

Despite recent advances in the field, treatment options for metastatic soft tissue sarcoma patients are limited. Eribulin, an antimitotic derived from the natural marine sponge product halichondrin B, is currently approved for the treatment of metastatic breast cancer. Following the promising activi...

Full description

Bibliographic Details
Main Authors:	Noujaim, Jonathan, Alam, Salma, Thway, Khin, Jones, Robin Lewis
Format:	Online
Language:	English
Published:	Medknow Publications & Media Pvt Ltd 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027783/

Similar Items

Eribulin mesylate in the treatment of metastatic breast cancer
by: Jain, Sarika, et al.
Published: (2012)

Eribulin in the management of inoperable soft-tissue sarcoma: patient selection and survival
by: Thomas, Colin, et al.
Published: (2016)

Epithelioid Sarcoma: Opportunities for Biology-Driven Targeted Therapy
by: Noujaim, Jonathan, et al.
Published: (2015)

Eribulin mesylate as a microtubule inhibitor for treatment of patients with metastatic breast cancer
by: Muñoz-Couselo, Eva, et al.
Published: (2011)

Eribulin mesylate in patients with refractory cancers: a Phase I study
by: Mukohara, Toru, et al.
Published: (2011)

Pharmacokinetics of eribulin mesylate in cancer patients with normal and impaired renal function
by: Tan, Antoinette R., et al.
Published: (2015)

Eribulin Mesylate Targets Human Telomerase Reverse Transcriptase in Ovarian Cancer Cells
by: Yamaguchi, Satoko, et al.
Published: (2014)

Endosialin expression in soft tissue sarcoma as a potential marker of undifferentiated mesenchymal cells
by: Thway, Khin, et al.
Published: (2016)

Dermatofibrosarcoma protuberans: from translocation to targeted therapy
by: Noujaim, Jonathan, et al.
Published: (2015)

First line palliative chemotherapy in elderly patients with advanced soft tissue sarcoma
by: Yousaf, Nadia, et al.
Published: (2015)

Phase I study of the halichondrin B analogue eribulin mesylate in combination with cisplatin in advanced solid tumors
by: Koczywas, M, et al.
Published: (2014)

Foreign Body Granulomas Induced by Intramuscular Leuprorelin Acetate Injection for Prostate Cancer: Clinical Mimics of Soft Tissue Sarcoma
by: Thway, Khin, et al.
Published: (2015)

Trabectedin in Soft Tissue Sarcomas
by: Petek, Bradley J., et al.
Published: (2015)

Targeted treatment for advanced soft tissue sarcoma: profile of pazopanib
by: Rajendra, Rajeev, et al.
Published: (2013)

Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma
by: De Sanctis, Rita, et al.
Published: (2015)

Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma [Corrigendum]
Published: (2016)

Advanced soft-tissue sarcoma and treatment options: critical appraisal of trabectedin
by: Desar, Ingrid M E, et al.
Published: (2016)

Efficacy and safety of pharmacological interventions in second- or later-line treatment of patients with advanced soft tissue sarcoma: a systematic review
by: Sharma, Sheetal, et al.
Published: (2013)

Eribulin for the treatment of metastatic breast cancer: an update on its safety and efficacy [Corrigendum]
Published: (2015)

Eribulin for the treatment of metastatic breast cancer: an update on its safety and efficacy
by: Doherty, Mark K, et al.
Published: (2015)

Systemic Therapy for Advanced Soft Tissue Sarcomas
by: Riedel, Richard F
Published: (2012)

Pazopanib in the management of advanced soft tissue sarcomas
by: Cranmer, Lee D, et al.
Published: (2016)

Trabectedin for advanced soft tissue sarcomas: optimizing use
by: Reid, Alison, et al.
Published: (2014)

A Case of Brain Metastases from Breast Cancer Treated with Whole-Brain Radiotherapy and Eribulin Mesylate
by: Nieder, Carsten, et al.
Published: (2012)

Eribulin Mesylate in Pretreated Breast Cancer Patients: A Multicenter Retrospective Observational Study
by: Gamucci, Teresa, et al.
Published: (2014)

Eribulin mesylate exerts specific gene expression changes in pericytes and shortens pericyte-driven capillary network in vitro
by: Agoulnik, Sergei I, et al.
Published: (2014)

Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models
by: Funahashi, Yasuhiro, et al.
Published: (2014)

Eribulin Mesylate Combined with Local Treatment for Brain Metastasis from Breast Cancer: Two Case Reports
by: Byun, Kyung-Do, et al.
Published: (2016)

Cost-Effectiveness of Pazopanib in Advanced Soft Tissue Sarcoma in the United Kingdom
by: Amdahl, Jordan, et al.
Published: (2014)

Effect of phentolamine mesylate on duration of soft tissue local anesthesia in children
by: Nourbakhsh, Nosrat, et al.
Published: (2012)

Phase II trial of eribulin mesylate as a first- or second-line treatment for locally advanced or metastatic breast cancer: a multicenter, single-arm trial
by: Tetsu Hayashida, et al.
Published: (2018-06-01)

Health-related quality of life in patients with locally advanced or metastatic breast cancer treated with eribulin mesylate or capecitabine in an open-label randomized phase 3 trial
by: Cortes, Javier, et al.
Published: (2015)

A phase I combination dose-escalation study of eribulin mesylate and gemcitabine in patients with advanced solid tumours: a study of the Princess Margaret Consortium
by: Lheureux, S, et al.
Published: (2015)

Phase 1 combination study of Eribulin mesylate with trastuzumab for advanced or recurrent human epidermal growth factor receptor 2 positive breast cancer
by: Mukai, Hirofumi, et al.
Published: (2014)

Subgroup Analyses from a Phase 3, Open-Label, Randomized Study of Eribulin Mesylate Versus Capecitabine in Pretreated Patients with Advanced or Metastatic Breast Cancer
by: Twelves, Chris, et al.
Published: (2016)

Tumour biology, metastatic sites and taxanes sensitivity as determinants of eribulin mesylate efficacy in breast cancer: results from the ERIBEX retrospective, international, multicenter study
by: Dell’Ova, Mélodie, et al.
Published: (2015)

Myoepithelial carcinoma of the paracecal mesentery: aggressive behavior of a rare neoplasm at an unusual anatomic site
by: Khin Thway, et al.
Published: (2017-03-01)

Eribulin for Advanced Breast Cancer: A Drug Evaluation
by: Shablak, Alaaeldin
Published: (2013)

Retroperitoneal soft tissue sarcoma
by: Zepeda, Ernesto, et al.
Published: (2007)

Soft tissue sarcomas of the kidney
by: Olivia Köhle, et al.
Published: (2015-03-01)