Mechanism of endonuclease cleavage by the HigB toxin

Bacteria encode multiple type II toxin–antitoxin modules that cleave ribosome-bound mRNAs in response to stress. All ribosome-dependent toxin family members structurally characterized to date adopt similar microbial RNase architectures despite possessing low sequence identities. Therefore, determini...

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Bibliographic Details
Main Authors: Schureck, Marc A., Repack, Adrienne, Miles, Stacey J., Marquez, Jhomar, Dunham, Christine M.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027501/