Suppression of Myostatin Stimulates Regenerative Potential of Injured Antigravitational Soleus Muscle in Mice under Unloading Condition

Effects of myostatin (MSTN)-suppression on the regeneration of injured skeletal muscle under unloading condition were investigated by using transgenic mice expressing a dominant-negative form of MSTN (MSTN-DN). Both MSTN-DN and wild-type (WT) mice were subjected to continuous hindlimb suspension (HS...

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Bibliographic Details
Main Authors: Ohno, Yoshitaka, Matsuba, Yusuke, Hashimoto, Naohiro, Sugiura, Takao, Ohira, Yoshinobu, Yoshioka, Toshitada, Goto, Katsumasa
Format: Online
Language:English
Published: Ivyspring International Publisher 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027186/