Broad activation of latent HIV-1 in vivo

Broad activation of latent HIV-1 in vivo

The ‘shock and kill' approach to cure human immunodeficiency virus (HIV) includes transcriptional induction of latent HIV-1 proviruses using latency-reversing agents (LRAs) with targeted immunotherapy to purge infected cells. The administration of LRAs (panobinostat or vorinostat) to HIV-1-infe...

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Bibliographic Details
Main Authors: Barton, Kirston, Hiener, Bonnie, Winckelmann, Anni, Rasmussen, Thomas Aagaard, Shao, Wei, Byth, Karen, Lanfear, Robert, Solomon, Ajantha, McMahon, James, Harrington, Sean, Buzon, Maria, Lichterfeld, Mathias, Denton, Paul W., Olesen, Rikke, Østergaard, Lars, Tolstrup, Martin, Lewin, Sharon R., Søgaard, Ole Schmeltz, Palmer, Sarah
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025526/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025526/

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