Intermittent Hypoxia Influences Alveolar Bone Proper Microstructure via Hypoxia-Inducible Factor and VEGF Expression in Periodontal Ligaments of Growing Rats

Intermittent hypoxia (IH) recapitulates morphological changes in the maxillofacial bones in children with obstructive sleep apnea (OSA). Recently, we found that IH increased bone mineral density (BMD) in the inter-radicular alveolar bone (reflecting enhanced osteogenesis) in the mandibular first mol...

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Bibliographic Details
Main Authors: Oishi, Shuji, Shimizu, Yasuhiro, Hosomichi, Jun, Kuma, Yoichiro, Maeda, Hideyuki, Nagai, Hisashi, Usumi-Fujita, Risa, Kaneko, Sawa, Shibutani, Naoki, Suzuki, Jun-ichi, Yoshida, Ken-ichi, Ono, Takashi
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025444/