The case test-negative design for studies of the effectiveness of influenza vaccine in inpatient settings

Background: The test-negative design (TND) to evaluate influenza vaccine effectiveness is based on patients seeking care for acute respiratory infection, with those who test positive for influenza as cases and the test-negatives serving as controls. This design has not been validated for the inpati...

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Bibliographic Details
Main Authors: Foppa, Ivo M, Ferdinands, Jill M, Chaves, Sandra S, Haber, Michael J, Reynolds, Sue B, Flannery, Brendan, Fry, Alicia M
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025336/