The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity

TRPM7 is a member of the Transient-Receptor-Potential Melastatin ion channel family. TRPM7 is a unique fusion protein of an ion channel and an α-kinase. Although mammalian TRPM7 is well characterized biophysically and its pivotal role in cancer, ischemia and cardiovascular disease is becoming increa...

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Bibliographic Details
Main Authors: Jansen, Chad, Sahni, Jaya, Suzuki, Sayuri, Horgen, F. David, Penner, Reinhold, Fleig, Andrea
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024298/