Presence of Vaccine-Derived Newcastle Disease Viruses in Wild Birds

Presence of Vaccine-Derived Newcastle Disease Viruses in Wild Birds

Our study demonstrates the repeated isolation of vaccine-derived Newcastle disease viruses from different species of wild birds across four continents from 1997 through 2014. The data indicate that at least 17 species from ten avian orders occupying different habitats excrete vaccine-derived Newcast...

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Main Authors: Ayala, Andrea J., Dimitrov, Kiril M., Becker, Cassidy R., Goraichuk, Iryna V., Arns, Clarice W., Bolotin, Vitaly I., Ferreira, Helena L., Gerilovych, Anton P., Goujgoulova, Gabriela V., Martini, Matheus C., Muzyka, Denys V., Orsi, Maria A., Scagion, Guilherme P., Silva, Renata K., Solodiankin, Olexii S., Stegniy, Boris T., Miller, Patti J., Afonso, Claudio L.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023329/
id pubmed-5023329
recordtype oai_dc
spelling pubmed-50233292016-09-27 Presence of Vaccine-Derived Newcastle Disease Viruses in Wild Birds Ayala, Andrea J. Dimitrov, Kiril M. Becker, Cassidy R. Goraichuk, Iryna V. Arns, Clarice W. Bolotin, Vitaly I. Ferreira, Helena L. Gerilovych, Anton P. Goujgoulova, Gabriela V. Martini, Matheus C. Muzyka, Denys V. Orsi, Maria A. Scagion, Guilherme P. Silva, Renata K. Solodiankin, Olexii S. Stegniy, Boris T. Miller, Patti J. Afonso, Claudio L. Research Article Our study demonstrates the repeated isolation of vaccine-derived Newcastle disease viruses from different species of wild birds across four continents from 1997 through 2014. The data indicate that at least 17 species from ten avian orders occupying different habitats excrete vaccine-derived Newcastle disease viruses. The most frequently reported isolates were detected among individuals in the order Columbiformes (n = 23), followed in frequency by the order Anseriformes (n = 13). Samples were isolated from both free-ranging (n = 47) and wild birds kept in captivity (n = 7). The number of recovered vaccine-derived viruses corresponded with the most widely utilized vaccines, LaSota (n = 28) and Hitchner B1 (n = 19). Other detected vaccine-derived viruses resembled the PHY-LMV2 and V4 vaccines, with five and two cases, respectively. These results and the ubiquitous and synanthropic nature of wild pigeons highlight their potential role as indicator species for the presence of Newcastle disease virus of low virulence in the environment. The reverse spillover of live agents from domestic animals to wildlife as a result of the expansion of livestock industries employing massive amounts of live virus vaccines represent an underappreciated and poorly studied effect of human activity on wildlife. Public Library of Science 2016-09-14 /pmc/articles/PMC5023329/ /pubmed/27626272 http://dx.doi.org/10.1371/journal.pone.0162484 Text en https://creativecommons.org/publicdomain/zero/1.0/ This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Ayala, Andrea J.
Dimitrov, Kiril M.
Becker, Cassidy R.
Goraichuk, Iryna V.
Arns, Clarice W.
Bolotin, Vitaly I.
Ferreira, Helena L.
Gerilovych, Anton P.
Goujgoulova, Gabriela V.
Martini, Matheus C.
Muzyka, Denys V.
Orsi, Maria A.
Scagion, Guilherme P.
Silva, Renata K.
Solodiankin, Olexii S.
Stegniy, Boris T.
Miller, Patti J.
Afonso, Claudio L.
spellingShingle Ayala, Andrea J.
Dimitrov, Kiril M.
Becker, Cassidy R.
Goraichuk, Iryna V.
Arns, Clarice W.
Bolotin, Vitaly I.
Ferreira, Helena L.
Gerilovych, Anton P.
Goujgoulova, Gabriela V.
Martini, Matheus C.
Muzyka, Denys V.
Orsi, Maria A.
Scagion, Guilherme P.
Silva, Renata K.
Solodiankin, Olexii S.
Stegniy, Boris T.
Miller, Patti J.
Afonso, Claudio L.
Presence of Vaccine-Derived Newcastle Disease Viruses in Wild Birds
author_facet Ayala, Andrea J.
Dimitrov, Kiril M.
Becker, Cassidy R.
Goraichuk, Iryna V.
Arns, Clarice W.
Bolotin, Vitaly I.
Ferreira, Helena L.
Gerilovych, Anton P.
Goujgoulova, Gabriela V.
Martini, Matheus C.
Muzyka, Denys V.
Orsi, Maria A.
Scagion, Guilherme P.
Silva, Renata K.
Solodiankin, Olexii S.
Stegniy, Boris T.
Miller, Patti J.
Afonso, Claudio L.
author_sort Ayala, Andrea J.
title Presence of Vaccine-Derived Newcastle Disease Viruses in Wild Birds
title_short Presence of Vaccine-Derived Newcastle Disease Viruses in Wild Birds
title_full Presence of Vaccine-Derived Newcastle Disease Viruses in Wild Birds
title_fullStr Presence of Vaccine-Derived Newcastle Disease Viruses in Wild Birds
title_full_unstemmed Presence of Vaccine-Derived Newcastle Disease Viruses in Wild Birds
title_sort presence of vaccine-derived newcastle disease viruses in wild birds
description Our study demonstrates the repeated isolation of vaccine-derived Newcastle disease viruses from different species of wild birds across four continents from 1997 through 2014. The data indicate that at least 17 species from ten avian orders occupying different habitats excrete vaccine-derived Newcastle disease viruses. The most frequently reported isolates were detected among individuals in the order Columbiformes (n = 23), followed in frequency by the order Anseriformes (n = 13). Samples were isolated from both free-ranging (n = 47) and wild birds kept in captivity (n = 7). The number of recovered vaccine-derived viruses corresponded with the most widely utilized vaccines, LaSota (n = 28) and Hitchner B1 (n = 19). Other detected vaccine-derived viruses resembled the PHY-LMV2 and V4 vaccines, with five and two cases, respectively. These results and the ubiquitous and synanthropic nature of wild pigeons highlight their potential role as indicator species for the presence of Newcastle disease virus of low virulence in the environment. The reverse spillover of live agents from domestic animals to wildlife as a result of the expansion of livestock industries employing massive amounts of live virus vaccines represent an underappreciated and poorly studied effect of human activity on wildlife.
publisher Public Library of Science
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023329/
_version_ 1613651797290778624

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