An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation

An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation

Emerging evidence suggests that inflammation has a key role in depression and suicidal behavior. The kynurenine pathway is involved in neuroinflammation and regulates glutamate neurotransmission. In the cerebrospinal fluid (CSF) of suicidal patients, levels of inflammatory cytokines and the kynureni...

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Bibliographic Details
Main Authors: Brundin, L, Sellgren, C M, Lim, C K, Grit, J, Pålsson, E, Landén, M, Samuelsson, M, Lundgren, K, Brundin, P, Fuchs, D, Postolache, T T, Traskman-Bendz, L, Guillemin, G J, Erhardt, S
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022080/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022080/

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