Childhood Trauma and COMT Genotype Interact to Increase Hippocampal Activation in Resilient Individuals

Both childhood trauma and a functional catechol-O-methyltransferase (COMT) genetic polymorphism have been associated with posttraumatic stress disorder (PTSD) and depression; however, it is still unclear whether the two interact and how this interaction relates to long-term risk or resilience. Imagi...

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Bibliographic Details
Main Authors: van Rooij, Sanne J. H., Stevens, Jennifer S., Ely, Timothy D., Fani, Negar, Smith, Alicia K., Kerley, Kimberly A., Lori, Adriana, Ressler, Kerry J., Jovanovic, Tanja
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021680/