The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response

The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response

For efficient replication, viruses have developed mechanisms to evade innate immune responses, including the antiviral type-I interferon (IFN-I) system. Nipah virus (NiV), a highly pathogenic member of the Paramyxoviridae family (genus Henipavirus), is known to encode for four P gene-derived viral p...

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Bibliographic Details
Main Authors: Bharaj, Preeti, Wang, Yao E., Dawes, Brian E., Yun, Tatyana E., Park, Arnold, Yen, Benjamin, Basler, Christopher F., Freiberg, Alexander N., Lee, Benhur, Rajsbaum, Ricardo
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021333/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021333/

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