SPARC overexpression combined with radiation retards angiogenesis by suppressing VEGF-A via miR-410 in human neuroblastoma cells

Neuroblastoma (NB) is the most common extracranial solid tumor in children and despite aggressive therapy survival rates remain low. One of the contributing factors for low survival rates is aggressive tumor angiogenesis, which is known to increase due to radiation, one of the standard therapies for...

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Bibliographic Details
Main Authors: Boyineni, Jerusha, Tanpure, Smita, Gnanamony, Manu, Antony, Reuben, Fernández, Karen S., Lin, Julian, Pinson, David, Gondi, Christopher S.
Format: Online
Language:English
Published: D.A. Spandidos 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021251/