The yeast Aft2 transcription factor determines selenite toxicity by controlling the low affinity phosphate transport system

The yeast Saccharomyces cerevisiae is employed as a model to study the cellular mechanisms of toxicity and defense against selenite, the most frequent environmental selenium form. We show that yeast cells lacking Aft2, a transcription factor that together with Aft1 regulates iron homeostasis, are hi...

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Bibliographic Details
Main Authors: Pérez-Sampietro, María, Serra-Cardona, Albert, Canadell, David, Casas, Celia, Ariño, Joaquín, Herrero, Enrique
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020356/