Orf Virus 002 Protein Targets Ovine Protein S100A4 and Inhibits NF-κB Signaling

Orf virus (ORFV), a member of Parapoxvirus, has evolved various strategies to modulate the immune responses of host cells. The ORFV-encoded protein ORFV002, a regulator factor, has been found to inhibit the acetylation of NF-κB-p65 by blocking phosphorylation of NF-κB-p65 at Ser276 and also to disru...

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Bibliographic Details
Main Authors: Chen, Daxiang, Zheng, Zewei, Xiao, Bin, Li, Wei, Long, Mingjian, Chen, Huiqin, Li, Ming, Rock, Daniel L., Hao, Wenbo, Luo, Shuhong
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020088/