Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

The tremendous pandemic potential of coronaviruses was demonstrated twice in the last decades by two global outbreaks of deadly pneumonia. Entry of coronaviruses into cells is mediated by the transmembrane spike glycoprotein S, which forms a trimer carrying receptor-binding and membrane fusion funct...

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Bibliographic Details
Main Authors: Walls, Alexandra C., Tortorici, M.Alejandra, Bosch, Berend-Jan, Frenz, Brandon, Rottier, Peter J.M., DiMaio, Frank, Rey, FĂ©lix A., Veesler, David
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018210/