Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16

Transmission of HIV across mucosal barriers accounts for the majority of HIV infections worldwide. Thus, efforts aimed at enhancing protective immunity at these sites are a top priority, including increasing virus-specific antibodies (Abs) and antiviral activity at mucosal sites. Mucin proteins, inc...

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Bibliographic Details
Main Authors: Gunn, Bronwyn, Schneider, Jeffrey, Shansab, Maryam, Bastian, Arangassery Rosemary, Fahrbach, Kelly, Smith, Archer, Mahan, Alison, Karim, Marcus, Licht, Anna, Zvonar, Ivan, Tedesco, Jacquelynn, Anderson, Meegan, Chapel, Anais, Suscovich, Todd, Malaspina, David, Streeck, Hendrik, Walker, Bruce D., Kim, Arthur, Lauer, Georg, Altfeld, Marcus, Pillai, Shiv, Szleifer, Igal, Kelleher, Neil L., Kiser, Patrick F., Hope, Thomas J., Alter, Galit
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017893/