A Novel Potential Positron Emission Tomography Imaging Agent for Vesicular Monoamine Transporter Type 2

In the early 1990s, 9-(+)-11C-dihydrotetrabenazine (9-(+)-11C-DTBZ) was shown to be a useful positron emission tomography (PET) imaging agent for various neurodegenerative disorders. Here, we described the radiosynthesis and evaluation of the 9-(+)-11C-DTBZ analog, 10-(+)-11C-DTBZ, as a vesicular mo...

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Bibliographic Details
Main Authors: Huang, Zih-Rou, Tsai, Chia-Ling, Huang, Ya-Yao, Shiue, Chyng-Yann, Tzen, Kai-Yuan, Yen, Ruoh-Fang, Hsin, Ling-Wei
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017712/