CXCR7/p-ERK-Signaling Is a Novel Target for Therapeutic Vasculogenesis in Patients with Coronary Artery Disease

Coronary artery disease (CAD) is characterized by insufficient vasculogenic response to ischemia, which is typically accompanied by dysfunction of endothelial outgrowth cells (EOCs). CXC chemokine receptor 7 (CXCR7) is a key modulator of the neovascularization of EOCs to perfusion defect area. Howev...

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Bibliographic Details
Main Authors: Cao, Zheng, Tong, Xinzhu, Xia, Wenhao, Chen, Long, Zhang, Xiaoyu, Yu, Bingbo, Yang, Zhen, Tao, Jun
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017667/