Resolving the contributions of two cooperative mechanisms to the DNA Binding of AGT
The O6‐alkylguanine DNA alkyltransferase (AGT) is a DNA repair enzyme that binds DNA with moderate cooperativity. This cooperativity is important for its search for alkylated bases. A structural model of the cooperative complex of AGT with DNA predicts short‐range interactions between nearest protei...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
John Wiley and Sons Inc.
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016775/ |