Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover*

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover*

Lysosomal acid lipase (LAL) is essential for the clearance of endocytosed cholesteryl ester and triglyceride-rich chylomicron remnants. Humans and mice with defective or absent LAL activity accumulate large amounts of cholesteryl esters and triglycerides in multiple tissues. Although chylomicrons al...

Full description

Bibliographic Details
Main Authors: Grumet, Lukas, Eichmann, Thomas O., Taschler, Ulrike, Zierler, Kathrin A., Leopold, Christina, Moustafa, Tarek, Radovic, Branislav, Romauch, Matthias, Yan, Cong, Du, Hong, Haemmerle, Guenter, Zechner, Rudolf, Fickert, Peter, Kratky, Dagmar, Zimmermann, Robert, Lass, Achim
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016185/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016185/

Similar Items