Direct Optofluidic Measurement of the Lipid Permeability of Fluoroquinolones

Quantifying drug permeability across lipid membranes is crucial for drug development. In addition, reduced membrane permeability is a leading cause of antibiotic resistance in bacteria, and hence there is a need for new technologies that can quantify antibiotic transport across biological membranes....

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Bibliographic Details
Main Authors: Cama, Jehangir, Schaich, Michael, Al Nahas, Kareem, Hernández-Ainsa, Silvia, Pagliara, Stefano, Keyser, Ulrich F.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015079/