YAP Subcellular Localization and Hippo Pathway Transcriptome Analysis in Pediatric Hepatocellular Carcinoma

Pediatric hepatocellular carcinoma (HCC) is a rare tumor which is associated with an extremely high mortality rate due to lack of effective chemotherapy. Recently, the Hippo pathway and its transcriptional co-activator Yes-associated protein (YAP) have been shown to play a role in hepatocyte prolife...

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Bibliographic Details
Main Authors: LaQuaglia, Michael J., Grijalva, James L., Mueller, Kaly A., Perez-Atayde, Antonio R., Kim, Heung Bae, Sadri-Vakili, Ghazaleh, Vakili, Khashayar
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015017/