Optimizing Immunization Strategies for the Induction of Antigen-Specific CD4 and CD8 T Cell Responses for Protection against Intracellular Parasites

Immunization strategies that generate either CD4 or CD8 T cell responses are relatively well described, but less is known with regard to optimizing regimens to induce both CD4 and CD8 memory T cells. Considering the importance of both CD4 and CD8 T cells in the control of intracellular pathogens suc...

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Bibliographic Details
Main Authors: Hofmeyer, Kimberly A., Duthie, Malcolm S., Laurance, John D., Favila, Michelle A., Van Hoeven, Neal, Coler, Rhea N., Reed, Steven G.
Format: Online
Language:English
Published: American Society for Microbiology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014921/