Cardiac action of the first G protein biased small molecule apelin agonist
Apelin peptide analogues displaying bias towards G protein signalling pathways have beneficial cardiovascular actions compared with the native peptide in humans in vivo. Our aim was to determine whether small molecule agonists could retain G protein bias. We have identified a biased small molecule,...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier Science
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012889/ |