Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations

Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations

In neurological disorders, both acute and chronic neural stress can disrupt cellular proteostasis, resulting in the generation of pathological protein. However in most cases, neurons adapt to these proteostatic perturbations by activating a range of cellular protective and repair responses, thus mai...

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Bibliographic Details
Main Authors: Mollereau, B., Rzechorzek, N.M., Roussel, B.D., Sedru, M., Van den Brink, D.M., Bailly-Maitre, B., Palladino, F., Medinas, D.B., Domingos, P.M., Hunot, S., Chandran, S., Birman, S., Baron, T., Vivien, D., Duarte, C.B., Ryoo, H.D., Steller, H., Urano, F., Chevet, E., Kroemer, G., Ciechanover, A., Calabrese, E.J., Kaufman, R.J., Hetz, C.
Format: Online
Language:English
Published: Elsevier/North-Holland Biomedical Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010532/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010532/

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