Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms

Oligomerization of allergens plays an important role in IgE-mediated reactions, as effective crosslinking of IgE- FcεRI complexes on the cell membrane is dependent on the number of exposed B-cell epitopes in a single allergen molecule or on the occurrence of identical epitopes in a symmetrical arran...

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Bibliographic Details
Main Authors: Mares-Mejía, Israel, Martínez-Caballero, Siseth, Garay-Canales, Claudia, Cano-Sánchez, Patricia, Torres-Larios, Alfredo, Lara-González, Samuel, Ortega, Enrique, Rodríguez-Romero, Adela
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009318/