Pantoprazole, an FDA-approved proton-pump inhibitor, suppresses colorectal cancer growth by targeting T-cell-originated protein kinase

Pantoprazole, an FDA-approved proton-pump inhibitor, suppresses colorectal cancer growth by targeting T-cell-originated protein kinase

T-cell-originated protein kinase (TOPK) is highly expressed in several cancer cells and promotes tumorigenesis and progression, and therefore, it is an important target for drug treatment of tumor. Pantoprazole (PPZ) was identified to be a TOPK inhibitor from FDA-approved drug database by structure...

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Bibliographic Details
Main Authors: Zeng, Xiaoyu, Liu, Lin, Zheng, Mengzhu, Sun, Huimin, Xiao, Juanjuan, Lu, Tao, Huang, Guangqian, Chen, Pianpian, Zhang, Jianmin, Zhu, Feng, Li, Hua, Duan, Qiuhong
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008373/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008373/

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