N-Myc expression enhances the oncolytic effects of vesicular stomatitis virus in human neuroblastoma cells

N-Myc expression enhances the oncolytic effects of vesicular stomatitis virus in human neuroblastoma cells

N-myc oncogene amplification is associated but not present in all cases of high-risk neuroblastoma (NB). Since oncogene expression could often modulate sensitivity to oncolytic viruses, we wanted to examine if N-myc expression status would determine virotherapy efficacy to high-risk NB. We showed th...

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Bibliographic Details
Main Authors: Corredor, Juan C, Redding, Nicole, Bloté, Karen, Robbins, Stephen M, Senger, Donna L, Bell, John C, Beaudry, Paul
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008254/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008254/

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