Molecular and cellular effects of a novel hydroxamate-based HDAC inhibitor – belinostat – in glioblastoma cell lines: a preliminary report
Histone deacetylase (HDAC) inhibitors are now intensively investigated as potential cytostatic agents in many malignancies. Here, we provide novel information concerning the influence of belinostat (Bel), a hydroxamate-based pan-HDAC inhibitor, on glioblastoma LN-229 and LN-18 cells. We found that L...
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Springer US
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007275/ |