Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis

This study provides the first evidence that the phosphate-responsive transcription factor Pho4 is vital for survival of Candida albicans to diverse and physiologically relevant stresses. Pho4 is important for C. albicans pathogenesis, and thus these findings illustrate how metabolic adaptation promo...

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Bibliographic Details
Main Authors: Ikeh, Mélanie A. C., Kastora, Stavroula L., Day, Alison M., Herrero-de-Dios, Carmen M., Tarrant, Emma, Waldron, Kevin J., Banks, A. Peter, Bain, Judith M., Lydall, David, Veal, Elizabeth A., MacCallum, Donna M., Erwig, Lars P., Brown, Alistair J. P., Quinn, Janet
Format: Online
Language:English
Published: The American Society for Cell Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007097/