Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy

Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy

Mutations in the ferritin light chain (FTL) gene cause the neurodegenerative disease neuroferritinopathy or hereditary ferritinopathy (HF). HF is characterized by a severe movement disorder and by the presence of nuclear and cytoplasmic iron-containing ferritin inclusion bodies (IBs) in glia and neu...

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Main Authors: Garringer, Holly J., Irimia, Jose M., Li, Wei, Goodwin, Charles B., Richine, Briana, Acton, Anthony, Chan, Rebecca J., Peacock, Munro, Muhoberac, Barry B., Ghetti, Bernardino, Vidal, Ruben
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004847/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004847/

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