Polyurethane scaffolds seeded with CD34+ cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors

Polyurethane scaffolds seeded with CD34+ cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors

We describe a 3D erythroid culture system that utilises a porous polyurethane (PU) scaffold to mimic the compartmentalisation found in the bone marrow. PU scaffolds seeded with peripheral blood CD34+ cells exhibit a remarkable reproducibility of egress, with an increased output when directly compare...

Full description

Bibliographic Details
Main Authors: Severn, Charlotte E., Macedo, Hugo, Eagle, Mark J., Rooney, Paul, Mantalaris, Athanasios, Toye, Ashley M.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004174/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004174/

Similar Items