Evaluation of Different Normalization and Analysis Procedures for Illumina Gene Expression Microarray Data Involving Small Changes

While Illumina microarrays can be used successfully for detecting small gene expression changes due to their high degree of technical replicability, there is little information on how different normalization and differential expression analysis strategies affect outcomes. To evaluate this, we assess...

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Bibliographic Details
Main Authors: Johnstone, Daniel M., Riveros, Carlos, Heidari, Moones, Graham, Ross M., Trinder, Debbie, Berretta, Regina, Olynyk, John K., Scott, Rodney J., Moscato, Pablo, Milward, Elizabeth A.
Format: Online
Language:English
Published: MDPI 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003482/