Decreased Myelinated Fibers in the Hippocampal Dentate Gyrus of the Tg2576 Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD), the most common cause of dementia in the elderly, is characterized by deficits in cognition and memory. Although amyloid-β (Aβ) accumulation is known to be the earliest pathological event that triggers subsequent neurodegeneration, how Aβ accumulation causes behavioral defi...

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Bibliographic Details
Main Authors: Lu, Wei, Yang, Shu, Zhang, Lei, Chen, Lin, Chao, Feng-Lei, Luo, Yan-min, Xiao, Qian, Gu, Heng-Wei, Jiang, Rong, Tang, Yong
Format: Online
Language:English
Published: Bentham Science Publishers 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002931/