Work-Family Life Courses and Metabolic Markers in the MRC National Survey of Health and Development

The aim was to investigate whether the combined work-family life courses of British men and women were associated with differences in metabolic markers—waist circumference, blood pressure, high density lipoprotein cholesterol, triglycerides, and glycated haemoglobin—in mid-life. We used data from th...

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Main Authors:	Lacey, Rebecca E., Kumari, Meena, Sacker, Amanda, Stafford, Mai, Kuh, Diana, McMunn, Anne
Format:	Online
Language:	English
Published:	Public Library of Science 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001719/

id	pubmed-5001719
recordtype	oai_dc
spelling	pubmed-50017192016-09-12 Work-Family Life Courses and Metabolic Markers in the MRC National Survey of Health and Development Lacey, Rebecca E. Kumari, Meena Sacker, Amanda Stafford, Mai Kuh, Diana McMunn, Anne Research Article The aim was to investigate whether the combined work-family life courses of British men and women were associated with differences in metabolic markers—waist circumference, blood pressure, high density lipoprotein cholesterol, triglycerides, and glycated haemoglobin—in mid-life. We used data from the Medical Research Council’s National Survey of Health and Development—the 1946 British birth cohort. Multi-channel sequence analysis was used to create a typology of eight work-family life course types combining information on work, partnerships and parenthood between ages 16–51. Linear regression tested associations between work-family types and metabolic outcomes at age 53 on multiply imputed data (20 imputations) of >2,400 participants. Compared with men with strong ties to employment and early transitions to family life, men who made later transitions to parenthood and maintained strong ties to paid work had smaller waist circumferences (-2.16cm, 95% CI: -3.73, -0.59), lower triglycerides (9.78% lower, 95% CI: 0.81, 17.94) and lower blood pressure (systolic: -4.03mmHg, 95% CI: -6.93, -1.13; diastolic: -2.34mmHg, 95% CI: -4.15, -0.53). Married men and women who didn’t have children had increased high density lipoprotein cholesterol (7.23% higher, 95% CI: 0.68, 14.21) and lower waist circumferences (-4.67cm, 95% CI: -8.37, -0.97), respectively. For men later transitions to parenthood combined with strong ties to paid work were linked to reduced metabolic risk in mid-life. Fewer differences between work-family types and metabolic markers were seen for women. Public Library of Science 2016-08-26 /pmc/articles/PMC5001719/ /pubmed/27563726 http://dx.doi.org/10.1371/journal.pone.0161923 Text en © 2016 Lacey et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Lacey, Rebecca E. Kumari, Meena Sacker, Amanda Stafford, Mai Kuh, Diana McMunn, Anne
spellingShingle	Lacey, Rebecca E. Kumari, Meena Sacker, Amanda Stafford, Mai Kuh, Diana McMunn, Anne Work-Family Life Courses and Metabolic Markers in the MRC National Survey of Health and Development
author_facet	Lacey, Rebecca E. Kumari, Meena Sacker, Amanda Stafford, Mai Kuh, Diana McMunn, Anne
author_sort	Lacey, Rebecca E.
title	Work-Family Life Courses and Metabolic Markers in the MRC National Survey of Health and Development
title_short	Work-Family Life Courses and Metabolic Markers in the MRC National Survey of Health and Development
title_full	Work-Family Life Courses and Metabolic Markers in the MRC National Survey of Health and Development
title_fullStr	Work-Family Life Courses and Metabolic Markers in the MRC National Survey of Health and Development
title_full_unstemmed	Work-Family Life Courses and Metabolic Markers in the MRC National Survey of Health and Development
title_sort	work-family life courses and metabolic markers in the mrc national survey of health and development
description	The aim was to investigate whether the combined work-family life courses of British men and women were associated with differences in metabolic markers—waist circumference, blood pressure, high density lipoprotein cholesterol, triglycerides, and glycated haemoglobin—in mid-life. We used data from the Medical Research Council’s National Survey of Health and Development—the 1946 British birth cohort. Multi-channel sequence analysis was used to create a typology of eight work-family life course types combining information on work, partnerships and parenthood between ages 16–51. Linear regression tested associations between work-family types and metabolic outcomes at age 53 on multiply imputed data (20 imputations) of >2,400 participants. Compared with men with strong ties to employment and early transitions to family life, men who made later transitions to parenthood and maintained strong ties to paid work had smaller waist circumferences (-2.16cm, 95% CI: -3.73, -0.59), lower triglycerides (9.78% lower, 95% CI: 0.81, 17.94) and lower blood pressure (systolic: -4.03mmHg, 95% CI: -6.93, -1.13; diastolic: -2.34mmHg, 95% CI: -4.15, -0.53). Married men and women who didn’t have children had increased high density lipoprotein cholesterol (7.23% higher, 95% CI: 0.68, 14.21) and lower waist circumferences (-4.67cm, 95% CI: -8.37, -0.97), respectively. For men later transitions to parenthood combined with strong ties to paid work were linked to reduced metabolic risk in mid-life. Fewer differences between work-family types and metabolic markers were seen for women.
publisher	Public Library of Science
publishDate	2016
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001719/
_version_	1613637545408593920

Work-Family Life Courses and Metabolic Markers in the MRC National Survey of Health and Development

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