Biochemical and genetic analysis of the role of the viral polymerase in enterovirus recombination

Genetic recombination in single-strand, positive-sense RNA viruses is a poorly understand mechanism responsible for generating extensive genetic change and novel phenotypes. By moving a critical cis-acting replication element (CRE) from the polyprotein coding region to the 3′ non-coding region we ha...

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Bibliographic Details
Main Authors: Woodman, Andrew, Arnold, Jamie J., Cameron, Craig E., Evans, David J.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001610/