A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity

A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity

Aberrant mitochondrial fission plays a pivotal role in the pathogenesis of skeletal muscle insulin resistance. However, fusion-fission dynamics are physiologically regulated by inherent tissue-specific and nutrient-sensitive processes that may have distinct or even opposing effects with respect to i...

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Bibliographic Details
Main Authors: Tol, Marc J., Ottenhoff, Roelof, van Eijk, Marco, Zelcer, Noam, Aten, Jan, Houten, Sander M., Geerts, Dirk, van Roomen, Cindy, Bierlaagh, Marlou C., Scheij, Saskia, Hoeksema, Marten A., Aerts, Johannes M., Bogan, Jonathan S., Dorn, Gerald W., Argmann, Carmen A., Verhoeven, Arthur J.
Format: Online
Language:English
Published: American Diabetes Association 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001173/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001173/

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