Clinical and preclinical treatment of urologic diseases with phosphodiesterase isoenzymes 5 inhibitors: an update

Phosphodiesterase isoenzymes 5 inhibitors (PDE5-Is) are the first-line therapy for erectile dysfunction (ED). The constant discoveries of nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) cell-signaling pathway for smooth muscle (SM) control in other urogenital tracts (UGTs) make PDE5-Is promi...

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Bibliographic Details
Main Authors: Zhang, Wen-Hao, Zhang, Xin-Hua
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000795/