Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development

Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development

Proliferation and spatial development of colonic epithelial cells are highly regulated along the crypt vertical axis, which, when perturbed, can result in aberrant growth and carcinogenesis. In this study, two key factors were identified that have important and counterbalancing roles regulating thes...

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Bibliographic Details
Main Authors: Uchiyama, Kazuhiko, Sakiyama, Toshio, Hasebe, Takumu, Musch, Mark W., Miyoshi, Hiroyuki, Nakagawa, Yasushi, He, Tong-Chuan, Lichtenstein, Lev, Naito, Yuji, Itoh, Yoshito, Yoshikawa, Toshikazu, Jabri, Bana, Stappenbeck, Thaddeus, Chang, Eugene B.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999796/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999796/

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