Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation

Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation

Eukaryotic mRNAs often contain a Kozak sequence that helps tether the ribosome to the AUG start codon. The mRNA of histone H4 (h4) does not undergo classical ribosome scanning but has evolved a specific tethering mechanism. The cryo-EM structure of the rabbit ribosome complex with mouse h4 shows tha...

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Main Authors: Martin, Franck, Ménétret, Jean-François, Simonetti, Angelita, Myasnikov, Alexander G., Vicens, Quentin, Prongidi-Fix, Lydia, Natchiar, S. Kundhavai, Klaholz, Bruno P., Eriani, Gilbert
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999511/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999511/

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