Dihydroartemisinin induces endothelial cell anoikis through the activation of the JNK signaling pathway

Angiogenesis is required for the growth and metastasis of solid tumors. The anti-malarial agent dihydroartemisinin (DHA) demonstrates potent anti-angiogenic activity, but the underlying molecular mechanisms are not yet fully understood. During the process of angiogenesis, endothelial cells migrating...

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Bibliographic Details
Main Authors: Zhang, Jiao, Guo, Ling, Zhou, Xia, Dong, Fengyun, Li, Liqun, Cheng, Zuowang, Xu, Yinghua, Liang, Jiyong, Xie, Qi, Liu, Ju
Format: Online
Language:English
Published: D.A. Spandidos 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998146/