Fascin Regulates Nuclear Movement and Deformation in Migrating Cells

Fascin Regulates Nuclear Movement and Deformation in Migrating Cells

Fascin is an F-actin-bundling protein shown to stabilize filopodia and regulate adhesion dynamics in migrating cells, and its expression is correlated with poor prognosis and increased metastatic potential in a number of cancers. Here, we identified the nuclear envelope protein nesprin-2 as a bindin...

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Bibliographic Details
Main Authors: Jayo, Asier, Malboubi, Majid, Antoku, Susumu, Chang, Wakam, Ortiz-Zapater, Elena, Groen, Christopher, Pfisterer, Karin, Tootle, Tina, Charras, Guillaume, Gundersen, Gregg G., Parsons, Maddy
Format: Online
Language:English
Published: Cell Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997957/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997957/

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