Differential ERK1/2 Signaling and Hypertrophic Response to Endothelin-1 in Cardiomyocytes from SHR and Wistar-Kyoto Rats: A Potential Target for Combination Therapy of Hypertension
Extracellular signal regulated kinase½ (ERK1/2) signaling is critical to endothelin-1 (ET-1)-induced cardiomyocyte hypertrophy. This study was to investigate ERK1/2 signaling and hypertrophic response to ET-1 stimulation in cardiomyocytes (CMs) from spontaneous hypertensive rats (SHR) and normotensi...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Bentham Science Publishers
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997939/ |