Mesenchymal Stem Cells Reversed Morphine Tolerance and Opioid-induced Hyperalgesia

More than 240 million opioid prescriptions are dispensed annually to treat pain in the US. The use of opioids is commonly associated with opioid tolerance (OT) and opioid-induced hyperalgesia (OIH), which limit efficacy and compromise safety. The dearth of effective way to prevent or treat OT and OI...

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Bibliographic Details
Main Authors: Hua, Zhen, Liu, LiPing, Shen, Jun, Cheng, Katherine, Liu, Aijun, Yang, Jing, Wang, Lina, Qu, Tingyu, Yang, HongNa, Li, Yan, Wu, Haiyan, Narouze, John, Yin, Yan, Cheng, Jianguo
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995471/