Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1

Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1

Skeletal muscle atrophy, referred to as sarcopenia, is often observed in chronic kidney disease (CKD) patients, especially in patients who are undergoing hemodialysis. The purpose of this study was to determine whether uremic toxins are involved in CKD-related skeletal muscle atrophy. Among six prot...

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Bibliographic Details
Main Authors: Enoki, Yuki, Watanabe, Hiroshi, Arake, Riho, Sugimoto, Ryusei, Imafuku, Tadashi, Tominaga, Yuna, Ishima, Yu, Kotani, Shunsuke, Nakajima, Makoto, Tanaka, Motoko, Matsushita, Kazutaka, Fukagawa, Masafumi, Otagiri, Masaki, Maruyama, Toru
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994088/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994088/

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