Cognitive deficits caused by a disease-mutation in the α3 Na+/K+-ATPase isoform

Cognitive deficits caused by a disease-mutation in the α3 Na+/K+-ATPase isoform

The Na+/K+-ATPases maintain Na+ and K+ electrochemical gradients across the plasma membrane, a prerequisite for electrical excitability and secondary transport in neurons. Autosomal dominant mutations in the human ATP1A3 gene encoding the neuron-specific Na+/K+-ATPase α3 isoform cause different neur...

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Bibliographic Details
Main Authors: Holm, Thomas Hellesøe, Isaksen, Toke Jost, Glerup, Simon, Heuck, Anders, Bøttger, Pernille, Füchtbauer, Ernst-Martin, Nedergaard, Steen, Nyengaard, Jens Randel, Andreasen, Mogens, Nissen, Poul, Lykke-Hartmann, Karin
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994072/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994072/

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