IL-6-Producing, Noncatecholamines Secreting Pheochromocytoma Presenting as Fever of Unknown Origin

IL-6-Producing, Noncatecholamines Secreting Pheochromocytoma Presenting as Fever of Unknown Origin

Fever of unknown origin (FUO) can be an unusual first clinical manifestation of pheochromocytoma. Pheochromocytomas are tumors that may produce a variety of substances in addition to catecholamines. To date, several cases of IL-6-producing pheochromocytomas have been reported. This report describes...

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Main Authors: Ciacciarelli, Marco, Bellini, Davide, Laghi, Andrea, Polidoro, Alessandro, Pacelli, Antonio, Bottaccioli, Anna Giulia, Palmaccio, Giuseppina, Stefanelli, Federica, Clemenzi, Piera, Carini, Luisa, Iuliano, Luigi, Alessandri, Cesare
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992526/
id pubmed-4992526
recordtype oai_dc
spelling pubmed-49925262016-08-30 IL-6-Producing, Noncatecholamines Secreting Pheochromocytoma Presenting as Fever of Unknown Origin Ciacciarelli, Marco Bellini, Davide Laghi, Andrea Polidoro, Alessandro Pacelli, Antonio Bottaccioli, Anna Giulia Palmaccio, Giuseppina Stefanelli, Federica Clemenzi, Piera Carini, Luisa Iuliano, Luigi Alessandri, Cesare Case Report Fever of unknown origin (FUO) can be an unusual first clinical manifestation of pheochromocytoma. Pheochromocytomas are tumors that may produce a variety of substances in addition to catecholamines. To date, several cases of IL-6-producing pheochromocytomas have been reported. This report describes a 45-year-old woman with pheochromocytoma who was admitted with FUO, normal blood pressure levels, microcytic and hypochromic anemia, thrombocytosis, hyperfibrinogenemia, hypoalbuminemia, and normal levels of urine and plasma metanephrines. After adrenalectomy, fever and all inflammatory findings disappeared. Hindawi Publishing Corporation 2016 2016-08-07 /pmc/articles/PMC4992526/ /pubmed/27579040 http://dx.doi.org/10.1155/2016/3489046 Text en Copyright © 2016 Marco Ciacciarelli et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Ciacciarelli, Marco
Bellini, Davide
Laghi, Andrea
Polidoro, Alessandro
Pacelli, Antonio
Bottaccioli, Anna Giulia
Palmaccio, Giuseppina
Stefanelli, Federica
Clemenzi, Piera
Carini, Luisa
Iuliano, Luigi
Alessandri, Cesare
spellingShingle Ciacciarelli, Marco
Bellini, Davide
Laghi, Andrea
Polidoro, Alessandro
Pacelli, Antonio
Bottaccioli, Anna Giulia
Palmaccio, Giuseppina
Stefanelli, Federica
Clemenzi, Piera
Carini, Luisa
Iuliano, Luigi
Alessandri, Cesare
IL-6-Producing, Noncatecholamines Secreting Pheochromocytoma Presenting as Fever of Unknown Origin
author_facet Ciacciarelli, Marco
Bellini, Davide
Laghi, Andrea
Polidoro, Alessandro
Pacelli, Antonio
Bottaccioli, Anna Giulia
Palmaccio, Giuseppina
Stefanelli, Federica
Clemenzi, Piera
Carini, Luisa
Iuliano, Luigi
Alessandri, Cesare
author_sort Ciacciarelli, Marco
title IL-6-Producing, Noncatecholamines Secreting Pheochromocytoma Presenting as Fever of Unknown Origin
title_short IL-6-Producing, Noncatecholamines Secreting Pheochromocytoma Presenting as Fever of Unknown Origin
title_full IL-6-Producing, Noncatecholamines Secreting Pheochromocytoma Presenting as Fever of Unknown Origin
title_fullStr IL-6-Producing, Noncatecholamines Secreting Pheochromocytoma Presenting as Fever of Unknown Origin
title_full_unstemmed IL-6-Producing, Noncatecholamines Secreting Pheochromocytoma Presenting as Fever of Unknown Origin
title_sort il-6-producing, noncatecholamines secreting pheochromocytoma presenting as fever of unknown origin
description Fever of unknown origin (FUO) can be an unusual first clinical manifestation of pheochromocytoma. Pheochromocytomas are tumors that may produce a variety of substances in addition to catecholamines. To date, several cases of IL-6-producing pheochromocytomas have been reported. This report describes a 45-year-old woman with pheochromocytoma who was admitted with FUO, normal blood pressure levels, microcytic and hypochromic anemia, thrombocytosis, hyperfibrinogenemia, hypoalbuminemia, and normal levels of urine and plasma metanephrines. After adrenalectomy, fever and all inflammatory findings disappeared.
publisher Hindawi Publishing Corporation
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992526/
_version_ 1613631476329349120

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