Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression

ErbB3, a member of the ErbB family receptors, has a key role in the development and progression of several cancers, including non-small cell lung cancer (NSCLC), and in the establishment of resistance to therapies, leading to the development of anti-ErbB3 therapies.

Bibliographic Details
Main Authors: Ciardiello, Chiara, Roca, Maria Serena, Noto, Alessia, Bruzzese, Francesca, Moccia, Tania, Vitagliano, Carlo, Gennaro, Elena Di, Ciliberto, Gennaro, Roscilli, Giuseppe, Aurisicchio, Luigi, Marra, Emanuele, Mancini, Rita, Budillon, Alfredo, Leone, Alessandra
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991401/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991401/

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